Initial geminates in Leti: Consequences for moraic theory

published or submitted for publicationis peer reviewe

IS INJURY OCCURRENCE ASSOCIATED WITH JOINT COUPLING VARIABILITY DURING UNANTICIPATED MOVEMENT TASKS PERFORMED BY NETBALLERS?

This study determined whether lower extremity joint coupling variability (JCV) measures during unanticipated change of direction movements were associated with prospective lower limb injury occurrence in netballers. Twelve elite injury-free female netballers performed five trials of unanticipated sprinting tasks (straight sprints and sprints with a 180° turn on their dominant and non-dominant legs) in the motion analysis laboratory from a 10 m approach. Lower extremity JCV measures were calculated for all movement tasks from 3D data. All netballers were monitored prospectively for a period of six months for the occurrence of lower limb injury. Five (42%) netballers sustained an injury with all injuries on their dominant leg. Low joint coupling variability was associated with injury occurrence in elite female netballers (r = 0.66)

Markedness: A Predictability-Based Approach

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Loss of the DNA methyltransferase MET1 Induces H3K9 hypermethylation at PcG target genes and redistribution of H3K27 trimethylation to transposons in Arabidopsis thaliana.

Dimethylation of histone H3 lysine 9 (H3K9m2) and trimethylation of histone H3 lysine 27 (H3K27m3) are two hallmarks of transcriptional repression in many organisms. In Arabidopsis thaliana, H3K27m3 is targeted by Polycomb Group (PcG) proteins and is associated with silent protein-coding genes, while H3K9m2 is correlated with DNA methylation and is associated with transposons and repetitive sequences. Recently, ectopic genic DNA methylation in the CHG context (where H is any base except G) has been observed in globally DNA hypomethylated mutants such as met1, but neither the nature of the hypermethylated loci nor the biological significance of this epigenetic phenomenon have been investigated. Here, we generated high-resolution, genome-wide maps of both H3K9m2 and H3K27m3 in wild-type and met1 plants, which we integrated with transcriptional data, to explore the relationships between these two marks. We found that ectopic H3K9m2 observed in met1 can be due to defects in IBM1-mediated H3K9m2 demethylation at some sites, but most importantly targets H3K27m3-marked genes, suggesting an interplay between these two silencing marks. Furthermore, H3K9m2/DNA-hypermethylation at these PcG targets in met1 is coupled with a decrease in H3K27m3 marks, whereas CG/H3K9m2 hypomethylated transposons become ectopically H3K27m3 hypermethylated. Our results bear interesting similarities with cancer cells, which show global losses of DNA methylation but ectopic hypermethylation of genes previously marked by H3K27m3

Basics of Language for Language Learners

Second editionTools and Strategies for Language Learning -- Sounding Like a Native Speaker -- Thinking Like a Native Speaker -- Acting Like a Native SpeakerItem not openly available